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Abstract During spring 2011, an extreme flood occurred along the Richelieu River located in southern Quebec, Canada. The Richelieu River is the last section of the complex Richelieu basin, which is composed of the large Lake Champlain located in a valley between two large mountains. Previous attempts in reproducing the Richelieu River flow relied on the use of simplified lumped models and showed mixed results. In order to prepare a tool to assess accurately the change of flood recurrences in the future, a state‐of‐the‐art distributed hydrological model was applied over the Richelieu basin. The model setup comprises several novel methods and data sets such as a very high resolution river network, a modern calibration technique considering the net basin supply of Lake Champlain, a new optimization algorithm, and the use of an up‐to‐date meteorological data set to force the model. The results show that the hydrological model is able to satisfactorily reproduce the multiyear mean annual hydrograph and the 2011 flow time series when compared with the observed river flow and an estimation of the Lake Champlain net basin supply. Many factors, such as the quality of the meteorological forcing data, that are affected by the low density of the station network, the steep terrain, and the lake storage effect challenged the simulation of the river flow. Overall, the satisfactory validation of the hydrological model allows to move to the next step, which consists in assessing the impacts of climate change on the recurrence of Richelieu River floods. , Plain Language Summary In order to study the 2011 Richelieu flood and prepare a tool capable of estimating the effects of climate change on the recurrence of floods, a hydrological model is applied over the Richelieu basin. The application of a distributed hydrological model is useful to simulate the flow of all the tributaries of the Richelieu basin. This new model setup stands out from past models due to its distribution in several hydrological units, its high‐resolution river network, the calibration technique, and the high‐resolution weather forcing data set used to drive the model. The model successfully reproduced the 2011 Richelieu River flood and the annual hydrograph. The simulation of the Richelieu flow was challenging due to the contrasted elevation of the Richelieu basin and the presence of the large Lake Champlain that acts as a reservoir and attenuates short‐term fluctuations. Overall, the application was deemed satisfactory, and the tool is ready to assess the impacts of climate change on the recurrence of Richelieu River floods. , Key Points An advanced high‐resolution distributed hydrological model is applied over a U.S.‐Canada transboundary basin The simulated net basin supply of Lake Champlain and the Richelieu River discharge are in good agreement with observations of the 2011 flood The flow simulation is challenging due to the topographic and meteorological complexities of the basin and uncertainties in the observations